SEPIA: simulation-based evaluation of prioritization algorithms
نویسندگان
چکیده
منابع مشابه
Confidence-based Somatic Mutation Evaluation and Prioritization
Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation detection is prone to erroneous calls, with reported validation rates near 54% and congruence between algorithms less than 50%. Here, we developed an algorithm to assign a sin...
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We propose a new test case prioritization technique that combines both mutation-based and diversity-based approaches. Our diversity-aware mutation-based technique relies on the notion of mutant distinguishment, which aims to distinguish one mutant’s behavior from another, rather than from the original program. We empirically investigate the relative cost and effectiveness of the mutation-based ...
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Regression testing is an expensive, but important process in software testing. Unfortunately, there may be insufficient resources to allow for the re-execution of all test cases during regression testing. In this situation, test case prioritization techniques aim to improve the effectiveness of regression testing by ordering the test cases so that the most beneficial are executed first. In this...
متن کاملAn unbiased evaluation of gene prioritization tools
MOTIVATION Gene prioritization aims at identifying the most promising candidate genes among a large pool of candidates-so as to maximize the yield and biological relevance of further downstream validation experiments and functional studies. During the past few years, several gene prioritization tools have been defined, and some of them have been implemented and made available through freely ava...
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ژورنال
عنوان ژورنال: BMC Medical Informatics and Decision Making
سال: 2021
ISSN: 1472-6947
DOI: 10.1186/s12911-021-01536-4